Over the period of 1988-2016, numerous field and laboratory studies on peculiarities of formation and fulfillment of the biological potential of performance of winter and spring forms of triticale in comparison with other cereals were conducted against changing cultivation technology components and environmental conditions. Advantages of triticale, especially winter forms, were demonstrated in critical cultivattion regions. Physiologically active substances - antistress agents - enhance protective functions of plants and are a promising trend to increase resistance of crops to unfavorable environmental factors. Adaptive technologies of triticale cultivation contribute to fulfillment of biological potential and are economically and energetically grounded.