It was investigated the influence of biologically active substances of Linaria vulgaris (L.) Mill on endogenous regulators of apple trees, in order to use these substances in the organic plant cultivation. Phenolic glycosides (PhG), were obtained from the species of Linaria vulgaris (L.) Mill (linaroside), according to the developed procedure. The variety of ‘Michgla’ apple trees, cultivated under lysimeter conditions, was treated extra root with PhG aqueous solution, by spraying. Control trees were treated with water. The samples for biochemical analysis were collected during the most important phenological phases of the vegetation period: the initial phase of annual shoot growth, the phase of intensive growth and the bud formation phase.